TATI - Tübingen Ageing and Tumour Immunology Group

The Tübingen Ageing and Tumour Immunology Group (TATI) conducts research in human immunosenescence, vaccination, tumor immunity, immunotherapy, Alzheimer disease, longevity, immunity and aging. Our expertise is in polychromatic flow cytometry, T cell cloning, confocal microscopy, proteomics, signal transduction, hypoxia, antigen identification, immune monitoring, cancer vaccination, influenza vaccination.

Recent Publications

Pawelec G, Ostrand-Rosenberg S.

Professor Enrico Mihich, 1928-2016.

Cancer Immunol Immunother. 2017 Jul;66(7):955-957.  [Epub 2017 May 29]

Di Benedetto S, Müller L, Wenger E, Düzel S, Pawelec G.

Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions.

Neurosci Biobehav Rev. 2017 Apr;75:114-128. Review.  [Epub 2017 Feb 1]

Shipp C, Pawelec G.

The fifteenth International Conference on Progress in Vaccination against Cancer (PIVAC-15), 6-8 October 2015, Tübingen, Germany: looking back on 15 years of progress.

Cancer Immunol Immunother. 2017 Feb;66(2):273-279.   [Epub 2016 Aug 24]

Kini Bailur J, Gueckel B, Pawelec G.

Prognostic impact of high levels of circulating plasmacytoid dendritic cells in breast cancer.

J Transl Med. 2016 May 28;14(1):151.  [PubMed]

Waaijer ME, Westendorp RG, Goldeck D, Gunn DA, Pawelec G, Stijntjes M, Slagboom PE, Maier AB.

Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?

Exp Gerontol. 2017 Jan;87(Pt B):175-181.  [Epub 2016 Apr 2]

Wistuba-Hamprecht K, Martens A, Heubach F, Romano E, Geukes Foppen M, Yuan J, Postow M, Wong P, Mallardo D, Schilling B, Di Giacomo AM, Khammari A, Dreno B, Maio M, Schadendorf D, Ascierto PA, Wolchok JD, Blank CU, Garbe C, Pawelec G, Weide B.

Peripheral CD8 effector-memory type 1 T-cells correlate with outcome in ipilimumab-treated stage IV melanoma patients.

Eur J Cancer. 2017 Mar;73:61-70.  [Epub 2017 Feb 4]

Bailur JK, Pawelec G, Hatse S, Brouwers B, Smeets A, Neven P, Laenen A, Wildiers H, Shipp C.

Immune profiles of elderly breast cancer patients are altered by chemotherapy and relate to clinical frailty.

Breast Cancer Res. 2017 Feb 28;19(1):20.  [PubMed - in process]

Pawelec G.

Immunosenescence and cancer.

Biogerontology. 2017 Feb 20.  [Epub ahead of print]

There is a complete list of the publication since 2012 of the TATI Group on the website.

Recent and Future Activities

Nov 14, 2016: G. Pawelec: "Immunity and ageing: causes and consequences of immunosenescence in humans."

Departmental Seminar, Center for Aging, Tulane University, New Orleans, USA; invited by Prof. M. Jaswinski.

Oct 19, 2016: G. Pawelec:"Immune Parameters Associated with Mortality in the Elderly are Context-Dependent: Lessons from Sweden, Holland and Belgium."

Lecture at the Biology of Aging: Paving the way for healthy aging conference, Montreal, CAN;  invited by Prof. T. Fülöp. 

Sep 30-Oct 1, 2016: "Adult Vaccines European Futuring Collaborative" , organized by Pfizer in Zurich (SUI).

Interview with Prof. Pawelec  [Video].

Sep 26, 2016: G. Pawelec: "Clonal T cell cultures as models of immune cell ageing."

Lecture at the Cell Fates and Aging Conference, Dubrovnik-Cavtat, Croatia; invited by Profs. J. Campisi and J. Vijg.

Sep 23, 2016:  G. Pawelec:  "Immunosenescence and cancer."

Lecture at the 10th European Biogerontology Congress, Warsaw, PL; invited by Prof. E. Sikora.

Sep 16, 2016: G. Pawelec: "Immunotherapy of Cancer: Triumphs and Challenges."

Visiting Professor Lecture at Nottingham Trent University, Nottingham, UK; invited by Prof. G. Pockley. 

Aug 11, 2016: G. Pawelec: "Immunosenescence and Cancer: is there an 'Immune Risk Profile' in cancer and ageing?"

Lecture at Health Sciences North Research Institute, Sudbury, ON, Canada; invited by Dr J. McElhaney.

Aug 2, 2016: Kilian Wistuba-Hamprecht after the defence of his thesis.

Prof. Pawelec  put the hat on Kilian, while Prof. Rammensee was looking on with friends and colleagues.

Future Activities

G. Pawelec will be attending the following meetings in 2017:

(last update Mar 7, 2017) 

1.-5.4.  Washington DC (attending AACR Annual Meeting)

Prague (Keynote at CITIM)


Rome (speaking at Hematologic Diseases in the Elderly)


Barcelona (speaking at the EHA meeting)


Co-organiser of the Satellite Symposium on “Aging of the Immune System”


Washington DC (attending the AAI Annual Congress)


Paris (presenting at NICIS)


Chicago (attending FOCIS)



 Madrid (presenting ""A Clinical And Biological Perspective Of Human

 Myeloid-derived Suppressor cells in cancer" at the 22nd EHA conference)


 Exeter (presenting at the BSRA annual meeting


San Francisco (co-organising a session at the IAGG Conference)  


Loutraki, Greece (PIVAC 17)


Athens (presenting at “Molecular Aspects of Aging and Longevity”)

G. Pawelec will be attending the following meetings in 2018:

(last update November 18, 2016)



Austin, TX (co-organizer of the Keystone Symposium "Aging, Inflammation and  Immunity")


You can find a complete list of  recent activites  or  previous activities  on this website.