TATI - Tübingen Ageing and Tumour Immunology Group

The Tübingen Ageing and Tumour Immunology Group (TATI) conducts research in human immunosenescence, vaccination, tumor immunity, immunotherapy, Alzheimer disease, longevity, immunity and aging. Our expertise is in polychromatic flow cytometry, T cell cloning, confocal microscopy, proteomics, signal transduction, hypoxia, antigen identification, immune monitoring, cancer vaccination, influenza vaccination.

Recent Publications

Sansoni P, Vescovini R, Fagnoni FF, Akbar A, Arens R, Chiu YL, Cicin-Šain L, Dechanet-Merville J, Derhovanessian E, Ferrando-Martinez S, Franceschi C, Frasca D, Fülöp T, Furman D, Gkrania-Klotsas E, Goodrum F, Grubeck-Loebenstein B, Hurme M, Kern F, Lilleri D, López-Botet M, Maier AB, Marandu T, Marchant A, Matheï C, Moss P, Muntasell A, Remmerswaal EB, Riddell NE, Rothe K, Sauce D, Shin EC, Simanek AM, Smithey MJ, Söderberg-Nauclér C, Solana R, Thomas PG, van Lier R, Pawelec G, Nikolich-Zugich J.

New advances in CMV and immunosenescence.

Exp Gerontol. 2014 Apr 3. pii: S0531-5565(14)00092-8.  [Epub ahead of print]

Adriaensen W, Derhovanessian E, Vaes B, Van Pottelbergh G, Degryse JM, Pawelec G, Hamprecht K, Theeten H, Matheï C.

CD4:8 Ratio >5 Is Associated With a Dominant Naive T-Cell Phenotype and Impaired Physical Functioning in CMV-Seropositive Very Elderly People: Results From the BELFRAIL Study.

J Gerontol A Biol Sci Med Sci. 2014 Feb 25. [Epub ahead of print]

Faragher R, Frasca D, Remarque E, Pawelec G; for the ImAginE Consortium.

Better immunity in later life: a position paper.
Age (Dordr). 2014 Feb 16. [Epub ahead of print]

Fulop T, Larbi A, Witkowski JM, Kotb R, Hirokawa K, Pawelec G.

Immunosenescence and cancer.

Crit Rev Oncog. 2013;18(6):489-513. [PubMed]

There is a complete list of the publication since 2012 of the TATI Group on the website.

Recent and Future Activities

First RiskImmune meeting Feb 15, 2014.

Feb 15, 2014: RiskImmune

The majority of potential partners struggled through the atmospheric storms to London to brainstorm the RiskImmune proposal. RiskImmune was eventually submitted by G. Pawelec in response to the EC Horizon 2020 PHC-1 first Call on March 11, 2014.

BASE II Consortium, March 2014  (C) MPIB / Rossbach.
BASE II Consortium, March 2014 (C) MPIB / Rossbach.

March 6 & 7, 2014: BASE II Meeting in Berlin.

Evelyna Derhovanessian and Graham Pawelec attended the BASE-II meeting  and presented data on correlations between immune phenotypes, CMV and socieconomic status of the BASE-II subjects.

Julia Humes with Chris Shipp, her supervisor.

Jan-March 2014: Julia Humes,

an ERASMUS student from the University of Newcastle, completed her Bachelor thesis in the TATI group. Her thesis focused on the characterisation of pH regulatory proteins in melanoma.

Apr 27-30, 2014: CSC 2014 meeting in Rio das Pedras, Brazil.

G. Pawelec will be speaking at the CSC 2014 meeting.

May 6-8, 2104: CIMT 2014 in Mainz.

A. Martens and J. Kini will show their results on posters. J. Kini will give a short oral presentation: "Presence of circulating Her-2-reactive CD8 T-cells is associated with lower frequency of MDSCs and better survival in elderly breast cancer patients."

Sept 24-26, 2014: PIVAC 2014 in Rome.

G. Pawelec is on the organising committee of the PIVAC 2014 Annual Meeting (First Announcement).

Oct 2-5, 2014: Bulgarian Immunology Society Triennial Congress in Varna.

G. Pawelec will be speaking at the Bulgarian Immunology Society Triennial Congress.

Oct 9-11, 2014: Annual NIBIT meeting, Siena.

G. Pawelec will be speaking at the Annual NIBIT meeting 2014.

Dec 1-4, 2014: BSI Annual Congress in Brighton.

G. Pawelec is organising the session "Immune frailty and defence against infections" at the BSI Annual Congress 2014.

G. Pawelec will be attending the following meetings in 2014:

AACR, San Diego, April;
CIMT, Mainz, May;
ASCO, Chicago, May;
FOCIS, Chicago, June;
GSA, Washington DC, November.

You can find a complete list of future activites or previous activities on this website.