ESTDAB

European Searchable Tumour Cell and Data Bank

Description

Cost-shared infrastructure project coordinated by G. Pawelec

 

This project is supported by the European Commission within the Fifth Framework Infrastructures program

 

QLRI-CT2001-01325 (2001-2004)

 

ESTDAB provides a unique resource offering tumour cell lines to the cancer research community. It links a total of seven EU and NAS infrastructures to characterise and provide melanoma lines typed for immunologically and clinically-relevant parameters, ie. complete HLA class I and II molecular typing coupled with an assessment of the expression of MHC molecules at the cell surface; tumour antigen expression; adhesion / accessory molecule expression; secretion of and response to cytokines.

A multi-parameter searchable data base was developed based on the IMGT/HLA database

and made available on the Internet for searching by qualified investigators. Cells will be shipped to bona fide investigators requiring tumours expressing a particular constellation of the markers mentioned above. The two new NAS members will contribute to the characterisation of the cell lines (glycosylation patterns, cytokine and receptor polymorphisms).

Order Cell Lines

Order ESTDAB Melanoma Cell Lines using one of the following invoices:

Invoice sheet for ordering cell lines.
invoice_sheet_for_cell_lines.doc
Microsoft Word Document [147.5 KB]
Download
Invoice sheet for ordering cell lines
invoice_sheet_for_cell_lines.pdf
Adobe Acrobat Document [28.5 KB]
Download

Links

ESTDAB on CORDIS (Community Research & Development Information Service) of the EU.

http://cordis.europa.eu/project/rcn/58824_en.html

IPD: Immuno Polymorphism Database

IPD-ESTDAB provide a service enabling investigators to search online for HLA typed, immunologically characterised tumour cells.

http://www.ebi.ac.uk/ipd/estdab/index.html

 

IMGT / HLA database

http://www.ebi.ac.uk/ipd/imgt/hla/

Scientific Participants

Graham Pawelec

Section for Transplantation Immunology and Immunohaematology 
Zentrum für Medizinische Forschung 
Waldhörnlestr. 22 
D-72072 Tübingen, Federal Republic of Germany

I. Anthony Dodi

Anthony Nolan Research Institute
The Royal Free Hospital
Pond Street
Hampstead
London NW3 2QG, United Kingdom

Frederico Garrido

Dept. Analisis Clinicos & Immunology
Hospital Universitario Virgen de las Nieves
Avda. Fuerzas Armadas s/n
18014 Granada, Spain

Rolf Kiessling

IGT (Immune & Gene Therapy Laboratory
CCK (Cancer Center Karolinska)
KS-ringen R8:01
S-171 76 Stockholm, Sweden


Piotr Laidler

Institute of Medical Biochemistry
Jagiellonian University Medical College
ul. Kopernika 7
PL 35-034 Krakow, Poland


Steven G. E. Marsh

Anthony Nolan Research Institute
The Royal Free Hospital
Pond Street
Hampstead
London NW3 2QG, United Kingdom


Elissaveta Naumova

Central Laboratory of Clinical Immunology
University Hospital "Alexandrovska"
1 Georgy Sofiisky Street
1431 Sofia, Bulgaria


Per thor Straten

Tumor Immunology Group
Danish Cancer Society
Institute of Cancer Biology
Strandboulevarden 49
DK-2100 Copenhagen, Denmark

Picture from the 1st ESTDAB meeting in Tübingen in November 20, 2001 (from left to right): Front: F. Garrido, G. Pawelec, P. Straten, R. Kiessling,  Back: W. Wagner, L. Müller, T. Dodi, T. Marsh.
Picture from the 1st ESTDAB meeting in Tübingen in November 20, 2001 (from left to right): Front: F. Garrido, G. Pawelec, P. Straten, R. Kiessling, Back: W. Wagner, L. Müller, T. Dodi, T. Marsh.